CSN1S1 and TTBK1

Data Source:
HPRD (in vitro)

		CSN1S1	TTBK1
Description		casein alpha s1	tau tubulin kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Tau Protein Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Response To Estradiol Response To Progesterone Transmembrane Transport Response To Dehydroepiandrosterone Response To 11-deoxycorticosterone	Protein Phosphorylation Learning Or Memory Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Substantia Nigra Development Negative Regulation Of Protein Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Astrocyte Activation Positive Regulation Of Microglial Cell Activation Positive Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Cysteine-type Endopeptidase Activity
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS			Adult hearing difficulty ( 31564434) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Body size at age 10 ( 32376654) Diastolic blood pressure ( 29403010) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Hemoglobin ( 32888494) Mean arterial pressure ( 29403010) Pulse pressure ( 28739976) Red blood cell count ( 32888494) Systolic blood pressure ( 26390057 29403010 28739976)
Interacting Genes		11 interacting genes: CSNK2A1 CSNK2B HTRA2 PARK7 PLK1 PPM1J PRSS2 STK4 TOLLIP TTBK1 UBQLN2	5 interacting genes: CDK5R1 CSN1S1 MAP2 MAPT TUBB
Entrez ID		1446	84630
HPRD ID		00280	11653
Ensembl ID		ENSG00000126545	ENSG00000146216
Uniprot IDs		P47710	Q5TCY1
PDB IDs			4BTJ 4BTK 4BTM 4NFM 4NFN
Enriched GO Terms of Interacting Partners?
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