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FOXN1 and SPATC1L
Data Source:
BioGRID
(two hybrid)
FOXN1
SPATC1L
Description
forkhead box N1
spermatogenesis and centriole associated 1 like
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Cellular_component
Centrosome
Sperm Connecting Piece
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Molecular_function
Protein Binding
Protein Kinase A Regulatory Subunit Binding
Biological Process
Hair Follicle Development
T Cell Lineage Commitment
Regulation Of Transcription By RNA Polymerase II
Defense Response
Epidermis Development
Animal Organ Morphogenesis
Keratinocyte Differentiation
Positive Regulation Of Epithelial Cell Differentiation
Nail Development
T Cell Homeostasis
Positive Regulation Of Transcription By RNA Polymerase II
Blood Vessel Morphogenesis
Positive Regulation Of Hair Follicle Development
Lymphoid Lineage Cell Migration Into Thymus
Thymus Epithelium Morphogenesis
Regulation Of Positive Thymic T Cell Selection
Spermatogenesis
Biological_process
Actin Polymerization Or Depolymerization
Positive Regulation Of Protein Kinase A Signaling
Positive Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Drugs
Diseases
T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
GWAS
Bone mineral density (
31790847
)
Metabolite levels (
31628463
)
Tonsillectomy (
27182965
28928442
)
Interacting Genes
12 interacting genes:
CDA
CDC23
DMRT3
HOXA1
LHX8
MAPKBP1
PIN1
SPATC1L
TLE5
TRAF2
TRAPPC6A
TSSK1B
46 interacting genes:
ACOT7
ARL4A
ARMC7
ATPAF2
CABP2
DISC1
EXOSC8
FOXN1
FSD2
GOLGA6A
GTF3C6
HOOK2
IKZF1
KIFC3
KRT40
KRTAP5-9
LZTS2
MISP
MTUS2
MYO15B
NCK2
NUTF2
NXF1
PARN
PHC2
PHF11
PIAS2
PICK1
PNMA1
POLR1C
PPP1CB
PPP1CC
QARS1
RAD51D
RBMY1F
RBMY1J
REL
SIAH1
SYCE1
TCF4
TEKT4
TRIM27
TRMO
TSR2
UBL5
ZBTB8B
Entrez ID
8456
84221
HPRD ID
02907
10753
Ensembl ID
ENSG00000109101
ENSG00000160284
Uniprot IDs
O15353
Q9H0A9
PDB IDs
5OCN
6EL8
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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