FOXN1 and TSSK1B

Data Source:
BioGRID (two hybrid)

		FOXN1	TSSK1B
Description		forkhead box N1	testis specific serine kinase 1B
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Acrosomal Vesicle Nucleus Cytoplasm Motile Cilium
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Hair Follicle Development T Cell Lineage Commitment Regulation Of Transcription By RNA Polymerase II Defense Response Epidermis Development Animal Organ Morphogenesis Keratinocyte Differentiation Positive Regulation Of Epithelial Cell Differentiation Nail Development T Cell Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis Positive Regulation Of Hair Follicle Development Lymphoid Lineage Cell Migration Into Thymus Thymus Epithelium Morphogenesis Regulation Of Positive Thymic T Cell Selection	Protein Phosphorylation Multicellular Organism Development Spermatid Development Intracellular Signal Transduction
Pathways
Drugs			Fostamatinib
Diseases		T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
GWAS		Bone mineral density ( 31790847) Metabolite levels ( 31628463) Tonsillectomy ( 27182965 28928442)
Interacting Genes		12 interacting genes: CDA CDC23 DMRT3 HOXA1 LHX8 MAPKBP1 PIN1 SPATC1L TLE5 TRAF2 TRAPPC6A TSSK1B	8 interacting genes: CHEK2 EFS FAM229B FOXN1 MEOX2 TGFBR1 TGFBR2 TSKS
Entrez ID		8456	83942
HPRD ID		02907	11610
Ensembl ID		ENSG00000109101	ENSG00000212122
Uniprot IDs		O15353	A0ZT98 Q9BXA7
PDB IDs		5OCN 6EL8
Enriched GO Terms of Interacting Partners?
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