SRRM4 and CLK4

Data Source:
BioGRID (two hybrid)

		SRRM4	CLK4
Description		serine/arginine repetitive matrix 4	CDC like kinase 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	MRNA Binding Protein Binding Identical Protein Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing	Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)	Urate levels in obese individuals ( 25811787)
Interacting Genes		30 interacting genes: AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L2 LUZP4 MCRS1 RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SRRM1 SRSF11 TBC1D26 U2AF1 U2AF1L5 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1	12 interacting genes: CLASRP HSPB2 KPNA1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 RNF181 SRPK1 SRRM4 UBL5
Entrez ID		84530	57396
HPRD ID		13897	12140
Ensembl ID		ENSG00000139767	ENSG00000113240
Uniprot IDs		A7MD48 V5T9A0	Q9HAZ1
PDB IDs			6FYV
Enriched GO Terms of Interacting Partners?
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