CLK4 and SRRM4

Data Source:
BioGRID (two hybrid)

		CLK4	SRRM4
Description		CDC like kinase 4	serine/arginine repetitive matrix 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	MRNA Binding Protein Binding Identical Protein Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development Sensory Perception Of Sound RNA Splicing Cell Differentiation Neuron Maturation Regulation Of RNA Splicing
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Urate levels in obese individuals ( 25811787)	Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Facial morphology (factor 3, length of philtrum) ( 28441456) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Photic sneeze reflex ( 27182965) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		12 interacting genes: CLASRP HSPB2 KPNA1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 RNF181 SRPK1 SRRM4 UBL5	30 interacting genes: AKAP17A ARL6IP4 C16orf87 C1orf35 CACNA1A CDC37 CLK1 CLK4 FAM9B LUC7L2 LUZP4 MCRS1 RBM25 RBM39 RBMX2 RNPS1 RSRC1 SNIP1 SNRNP70 SRRM1 SRSF11 TBC1D26 U2AF1 U2AF1L5 WDR5 ZNF124 ZNF286A ZNF699 ZRSR2 ZRSR2P1
Entrez ID		57396	84530
HPRD ID		12140	13897
Ensembl ID		ENSG00000113240	ENSG00000139767
Uniprot IDs		Q9HAZ1	A7MD48 V5T9A0
PDB IDs		6FYV
Enriched GO Terms of Interacting Partners?
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