DHX16 and MEGF10

Data Source:
HPRD (two hybrid)

		DHX16	MEGF10
Description		DEAH-box helicase 16	multiple EGF like domains 10
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U2-type Precatalytic Spliceosome	Phagocytic Cup Plasma Membrane Integral Component Of Membrane Cell Projection
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269)	Alzheimer's disease (cognitive decline) ( 23535033) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)
Interacting Genes		10 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 SNRNP27 SNRNP40 XAB2	23 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1
Entrez ID		8449	84466
HPRD ID		04555	14384
Ensembl ID		ENSG00000204560	ENSG00000145794
Uniprot IDs		A0A1U9X7L7 B4DZ28 O60231 Q5SQH4	Q96KG7
PDB IDs		5Z56 5Z57 5Z58 6FF7
Enriched GO Terms of Interacting Partners?
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