MEGF10 and DHX16

Data Source:
HPRD (two hybrid)

		MEGF10	DHX16
Description		multiple EGF like domains 10	DEAH-box helicase 16
Image		No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Plasma Membrane Integral Component Of Membrane Cell Projection	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U2-type Precatalytic Spliceosome
	Molecular Function	Complement Component C1q Complex Binding Scavenger Receptor Activity Notch Binding	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity
	Biological Process	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Cell-cell Adhesion Muscle Cell Proliferation Homotypic Cell-cell Adhesion Apoptotic Cell Clearance Engulfment Of Apoptotic Cell Recognition Of Apoptotic Cell Myoblast Development Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Myoblast Migration Muscle Cell Development Apoptotic Process Involved In Development Positive Regulation Of Myoblast Proliferation	MRNA Splicing, Via Spliceosome RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Bone mineral content ( 31790847) Chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Hearing loss in Charcot-Marie-Tooth disease 1A ( 30958311) Initial pursuit acceleration ( 29064472) Response to antipsychotic treatment in schizophrenia ( 29503163)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269)
Interacting Genes		23 interacting genes: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 GULP1 HDAC4 ITSN2 MCF2L2 RANBP10 SART3 SCAPER SHTN1 SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1	10 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 SNRNP27 SNRNP40 XAB2
Entrez ID		84466	8449
HPRD ID		14384	04555
Ensembl ID		ENSG00000145794	ENSG00000204560
Uniprot IDs		Q96KG7	A0A1U9X7L7 B4DZ28 O60231 Q5SQH4
PDB IDs			5Z56 5Z57 5Z58 6FF7
Enriched GO Terms of Interacting Partners?
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