DHX16 and XAB2

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		DHX16	XAB2
Description		DEAH-box helicase 16	XPA binding protein 2
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GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleus Nucleoplasm Spliceosomal Complex U2-type Precatalytic Spliceosome	Prp19 Complex Nucleus Nucleoplasm Membrane Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Binding RNA Helicase Activity Protein Binding ATP Binding ATPase Activity	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Blastocyst Development Transcription-coupled Nucleotide-excision Repair Transcription, DNA-templated Cerebral Cortex Development
Pathways		mRNA Splicing - Major Pathway	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269)
Interacting Genes		10 interacting genes: APP APPBP2 COIL CSNK2A1 ESS2 HOMEZ MEGF10 SNRNP27 SNRNP40 XAB2	17 interacting genes: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 MIR106B MIR34B MIRLET7E MIRLET7G MIRLET7I POLR2A PPIE SMAD9 SUMO2 XPA
Entrez ID		8449	56949
HPRD ID		04555	18306
Ensembl ID		ENSG00000204560	ENSG00000076924
Uniprot IDs		A0A1U9X7L7 B4DZ28 O60231 Q5SQH4	Q9HCS7
PDB IDs		5Z56 5Z57 5Z58 6FF7	5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P
Enriched GO Terms of Interacting Partners?
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