NEURL4 and DBNL

Data Source:
HPRD (two hybrid, in vivo)

		NEURL4	DBNL
Description		neuralized E3 ubiquitin protein ligase 4	drebrin like
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GO Annotations	Cellular Component	Cytoplasm Centriole	Golgi Membrane Ruffle Podosome Extracellular Region Cytoplasm Early Endosome Cytosol Actin Filament Plasma Membrane Cell Cortex Postsynaptic Density Lamellipodium Dendrite Site Of Polarized Growth Clathrin-coated Vesicle Membrane Cortical Actin Cytoskeleton Secretory Granule Lumen Perikaryon Postsynaptic Membrane Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Actin Binding Protein Binding Protein C-terminus Binding Enzyme Activator Activity Protein Domain Specific Binding Cadherin Binding Actin Filament Binding
	Biological Process	Protein Ubiquitination	Adaptive Immune Response Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Synapse Assembly Rac Protein Signal Transduction Regulation Of Actin Filament Polymerization Neutrophil Degranulation Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Positive Regulation Of Dendritic Spine Morphogenesis Podosome Assembly Ruffle Assembly Postsynaptic Actin Cytoskeleton Organization
Pathways			Caspase-mediated cleavage of cytoskeletal proteins Neurexins and neuroligins Neutrophil degranulation
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 33536424)	Blood protein levels ( 30072576)
Interacting Genes		1 interacting genes: DBNL	12 interacting genes: ACD CASP3 HOMER1 MAP4K1 NEURL4 POT1 SH2D4A SH3BP2 SYK TERF1 TERF2IP ZAP70
Entrez ID		84461	28988
HPRD ID		13894	06588
Ensembl ID		ENSG00000215041	ENSG00000136279
Uniprot IDs		Q96JN8	B4DUF9 Q9UJU6
PDB IDs		2E63	1X67
Enriched GO Terms of Interacting Partners?
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