DBNL and NEURL4

Data Source:
HPRD (two hybrid, in vivo)

		DBNL	NEURL4
Description		drebrin like	neuralized E3 ubiquitin protein ligase 4
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GO Annotations	Cellular Component	Golgi Membrane Ruffle Podosome Extracellular Region Cytoplasm Early Endosome Cytosol Actin Filament Plasma Membrane Cell Cortex Postsynaptic Density Lamellipodium Dendrite Site Of Polarized Growth Clathrin-coated Vesicle Membrane Cortical Actin Cytoskeleton Secretory Granule Lumen Perikaryon Postsynaptic Membrane Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Cytoplasm Centriole
	Molecular Function	Actin Binding Protein Binding Protein C-terminus Binding Enzyme Activator Activity Protein Domain Specific Binding Cadherin Binding Actin Filament Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Adaptive Immune Response Receptor-mediated Endocytosis Activation Of JUN Kinase Activity Synapse Assembly Rac Protein Signal Transduction Regulation Of Actin Filament Polymerization Neutrophil Degranulation Positive Regulation Of Axon Extension Neuron Projection Morphogenesis Positive Regulation Of Dendritic Spine Morphogenesis Podosome Assembly Ruffle Assembly Postsynaptic Actin Cytoskeleton Organization	Protein Ubiquitination
Pathways		Caspase-mediated cleavage of cytoskeletal proteins Neurexins and neuroligins Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Systemic lupus erythematosus ( 33536424)
Interacting Genes		12 interacting genes: ACD CASP3 HOMER1 MAP4K1 NEURL4 POT1 SH2D4A SH3BP2 SYK TERF1 TERF2IP ZAP70	1 interacting genes: DBNL
Entrez ID		28988	84461
HPRD ID		06588	13894
Ensembl ID		ENSG00000136279	ENSG00000215041
Uniprot IDs		B4DUF9 Q9UJU6	Q96JN8
PDB IDs		1X67	2E63
Enriched GO Terms of Interacting Partners?
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