ABLIM2 and ATP6V0A1

Data Source:
BioGRID (two hybrid)

		ABLIM2	ATP6V0A1
Description		actin binding LIM protein family member 2	ATPase H+ transporting V0 subunit a1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	Metal Ion Binding Actin Filament Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Transcription, DNA-templated Lamellipodium Assembly Actin Cytoskeleton Organization	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Toxin Transport Proton Transmembrane Transport
Pathways		DCC mediated attractive signaling	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Cognitive function ( 28808816) Diffusing capacity of carbon monoxide ( 30694715) Early onset periodontitis x smoking status interaction ( 31537151) Irritable bowel syndrome ( 29626450) Post bronchodilator FEV1 in COPD ( 26634245) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Triacylglyceride levels ( 31551469)	Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: ABRA AHNAK2 ATP6V0A1 MLIP SREBF2 TTN	7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267
Entrez ID		84448	535
HPRD ID		10623	01886
Ensembl ID		ENSG00000163995	ENSG00000033627
Uniprot IDs		A0A140VK02 Q6H8Q1	Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs		1V6G 1WIG 2L3X
Enriched GO Terms of Interacting Partners?
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