ATP6V0A1 and SNX4

Data Source:
BioGRID (two hybrid)

		ATP6V0A1	SNX4
Description		ATPase H+ transporting V0 subunit a1	sorting nexin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane	Cytoplasm Cytoplasmic Dynein Complex Plasma Membrane Membrane SNARE Complex Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Toxin Transport Proton Transmembrane Transport	Protein Transport Endocytic Recycling Positive Regulation Of Histamine Secretion By Mast Cell
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Adult body size ( 32376654) Estimated glomerular filtration rate in non-diabetics ( 31451708) Urate levels ( 31578528)
Interacting Genes		7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267	18 interacting genes: AGK ARL6IP1 ATP6V0A1 BIN1 DGAT2L6 EGFR HIVEP1 INSR LEPR MAGEA6 PDGFRA PDGFRB PTPN5 SH3GLB1 SNX2 SNX6 SNX7 SUPT5H
Entrez ID		535	8723
HPRD ID		01886	09334
Ensembl ID		ENSG00000033627	ENSG00000114520
Uniprot IDs		Q53ET5 Q53X12 Q5CZH6 Q93050	O95219
PDB IDs
Enriched GO Terms of Interacting Partners?
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