ATP6V0A1 and ABLIM2

Data Source:
BioGRID (two hybrid)

		ATP6V0A1	ABLIM2
Description		ATPase H+ transporting V0 subunit a1	actin binding LIM protein family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane	Cytoplasm Actin Cytoskeleton
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding	Metal Ion Binding Actin Filament Binding
	Biological Process	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Toxin Transport Proton Transmembrane Transport	Transcription, DNA-templated Lamellipodium Assembly Actin Cytoskeleton Organization
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport	DCC mediated attractive signaling
Drugs		Tiludronic acid
Diseases
GWAS		Asthma ( 32296059) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Cognitive function ( 28808816) Diffusing capacity of carbon monoxide ( 30694715) Early onset periodontitis x smoking status interaction ( 31537151) Irritable bowel syndrome ( 29626450) Post bronchodilator FEV1 in COPD ( 26634245) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Triacylglyceride levels ( 31551469)
Interacting Genes		7 interacting genes: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 ZNF267	6 interacting genes: ABRA AHNAK2 ATP6V0A1 MLIP SREBF2 TTN
Entrez ID		535	84448
HPRD ID		01886	10623
Ensembl ID		ENSG00000033627	ENSG00000163995
Uniprot IDs		Q53ET5 Q53X12 Q5CZH6 Q93050	A0A140VK02 Q6H8Q1
PDB IDs			1V6G 1WIG 2L3X
Enriched GO Terms of Interacting Partners?
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