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TMEM101 and VAPB
Data Source:
BioGRID
(two hybrid)
TMEM101
VAPB
Description
transmembrane protein 101
VAMP associated protein B and C
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Integral Component Of Membrane
Golgi Membrane
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Golgi Apparatus
Plasma Membrane
Integral Component Of Membrane
Endoplasmic Reticulum Exit Site
Molecular Function
Protein Binding
Protein Binding
Microtubule Binding
Enzyme Binding
FFAT Motif Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Heterodimerization Activity
Beta-tubulin Binding
Biological Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Calcium Ion Homeostasis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Endoplasmic Reticulum Organization
Modulation By Virus Of Host Process
Sphingolipid Biosynthetic Process
Endoplasmic Reticulum Unfolded Protein Response
IRE1-mediated Unfolded Protein Response
Positive Regulation Of Viral Genome Replication
Endoplasmic Reticulum-plasma Membrane Tethering
COPII-coated Vesicle Budding
Endoplasmic Reticulum Membrane Organization
Pathways
Sphingolipid de novo biosynthesis
Drugs
Diseases
Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS
Interacting Genes
21 interacting genes:
BNIP3
C4orf3
CCR4
DRD2
GIMAP1
GPR182
MAP4K1
NDUFA3
NINJ2
NPSR1
PDZK1IP1
PKMYT1
STRIT1
STX10
SYNJ2BP
TMEM243
TMEM65
TMIE
VAMP1
VAMP2
VAPB
41 interacting genes:
AIG1
AQP2
AQP6
CD79A
CYB561
CYBRD1
EBAG9
EBP
ELOVL4
EMD
FAM174A
GLP1R
GPR25
HSD17B13
JAGN1
KCNB1
MTNR1A
OSBPL2
PTGES
REEP4
RETREG3
RMDN2
RNASEK
RNF111
SCN3B
SLC22A1
SLC35C2
STX1A
STX2
STX4
STX5
TMEM101
TMX2
TTC39B
USP20
VAMP1
VAMP2
VHL
VKORC1
ZBTB22
ZDHHC15
Entrez ID
84336
9217
HPRD ID
14623
09300
Ensembl ID
ENSG00000091947
ENSG00000124164
Uniprot IDs
B4DFS4
Q96IK0
O95292
Q53XM7
PDB IDs
2MDK
3IKK
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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