BRMS1L and RBBP7

Data Source:
HPRD (in vivo)

		BRMS1L	RBBP7
Description		BRMS1 like transcriptional repressor	RB binding protein 7, chromatin remodeling factor
Image		No pdb structure
GO Annotations	Cellular Component	Sin3-type Complex	Nucleus Nucleoplasm Cytosol NuRD Complex ESC/E(Z) Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Regulation Of Growth	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Post-translational Protein Modification Negative Regulation Of Gene Expression, Epigenetic Response To Steroid Hormone Negative Regulation Of G0 To G1 Transition Cellular Heat Acclimation Regulation Of Signal Transduction By P53 Class Mediator
Pathways			PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		22 interacting genes: ACTN2 AMOTL2 BRMS1 CEP70 CYTOR DEUP1 EXOC5 HDAC1 HDAC2 ING1 MCRS1 MID2 PBX1 PBX2 RBBP4 RBBP7 RBP1 SAP30 SIN3A TEX11 TULP3 TXLNA	34 interacting genes: APPL1 APPL2 BCL11A BCL11B BRCA1 BRMS1 BRMS1L BUB3 CREBBP CYTOR DHX30 ERCC6 ESR1 FOXK2 H3-4 H3C1 HDAC1 HDAC2 HUWE1 ING1 MBD3 MBD3L2 MTA2 NR2E3 PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1
Entrez ID		84312	5931
HPRD ID		16564	04231
Ensembl ID		ENSG00000100916	ENSG00000102054
Uniprot IDs		Q5PSV4	Q16576 Q6FHQ0
PDB IDs			3CFS 3CFV
Enriched GO Terms of Interacting Partners?
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