NR0B2 and EID1

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		NR0B2	EID1
Description		nuclear receptor subfamily 0 group B member 2	EP300 interacting inhibitor of differentiation 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Homodimerization Activity Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Transcription Regulator Inhibitor Activity	Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Regulator Activity Histone Acetyltransferase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Circadian Rhythm Cholesterol Metabolic Process Response To Glucose Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Bile Acid And Bile Salt Transport Animal Organ Regeneration Positive Regulation Of Insulin Secretion Circadian Regulation Of Gene Expression Negative Regulation Of DNA-binding Transcription Factor Activity Response To Ethanol Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Cell Differentiation Regulation Of Histone Acetylation Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068) LDL cholesterol ( 24097068) Triglycerides ( 24097068)
Interacting Genes		51 interacting genes: AR CHRD CIDEC DDX20 EID1 ESR1 ESR2 ESRRA ESRRG FN1 GPS2 GPSM3 HDAC3 HDAC6 HNF4A HNF4G HNRNPA1 ID2 IL3RA NCOA3 NEUROD1 NR1H2 NR1H3 NR1I2 NR1I3 NR3C1 NR5A2 PAX9 PEF1 PLSCR1 POLR2A PPARD PPARG RARA RARG RBP5 RNF31 RXRA RXRB RXRG SMAD4 SMARCA2 SMARCB1 SMARCE1 SNW1 THRA TP53 VDR XBP1 ZAP70 ZMYND10	18 interacting genes: ARID4A CREBBP EP300 H2AC8 H2BC3 H3C1 H4C1 KAT2A MDM2 NCOA2 NDN NR0B2 PCID2 PSEN2 RB1 TRIM27 UBE3A XRCC6
Entrez ID		8431	23741
HPRD ID		05219	06907
Ensembl ID		ENSG00000131910	ENSG00000255302
Uniprot IDs		Q15466	Q9Y6B2
PDB IDs		1YUC 2Q3Y 2Z4J 4DOR 4ONI 5UFS 6W9M
Enriched GO Terms of Interacting Partners?
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