EID1 and ARID4A

Data Source:
HPRD (in vivo, in vitro)

		EID1	ARID4A
Description		EP300 interacting inhibitor of differentiation 1	AT-rich interaction domain 4A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Cytosol Plasma Membrane Transcription Repressor Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Histone Acetyltransferase Regulator Activity Histone Acetyltransferase Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Cycle Cell Differentiation Regulation Of Histone Acetylation Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Regulation Of Gene Expression By Genetic Imprinting Regulation Of Transcription By RNA Polymerase II Spermatogenesis Histone H4-K20 Trimethylation Histone H3-K9 Trimethylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Erythrocyte Development Histone H3-K4 Trimethylation Establishment Of Sertoli Cell Barrier
Pathways			HDACs deacetylate histones Potential therapeutics for SARS
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30679032) Alcohol consumption in current drinkers ( 28937693) Brain morphology (MOSTest) ( 32665545) Coronary artery disease ( 29212778 33020668) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Problematic alcohol use ( 32451486) Venous thromboembolism ( 31420334) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		18 interacting genes: ARID4A CREBBP EP300 H2AC8 H2BC3 H3C1 H4C1 KAT2A MDM2 NCOA2 NDN NR0B2 PCID2 PSEN2 RB1 TRIM27 UBE3A XRCC6	15 interacting genes: BRMS1 CCNA2 CCNB1 CCND1 CCNE1 CDK1 CDK2 CDK4 EID1 H3C14 H4-16 HDAC1 HDAC2 HDAC3 SIN3A
Entrez ID		23741	5926
HPRD ID		06907	01575
Ensembl ID		ENSG00000255302	ENSG00000032219
Uniprot IDs		Q9Y6B2	A0A024R657 A0A024R680 A0A024R6A2 P29374 Q05CG0
PDB IDs			2LCC 2MAM 2YRV 6BPH
Enriched GO Terms of Interacting Partners?
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