GINS4 and KIF16B

Data Source:
BioGRID (two hybrid)

		GINS4	KIF16B
Description		GINS complex subunit 4	kinesin family member 16B
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GO Annotations	Cellular Component	GINS Complex Nucleoplasm Cytoplasm CMG Complex	Cytoplasm Endosome Early Endosome Spindle Cytosol Kinesin Complex Microtubule Early Endosome Membrane
	Molecular Function	Protein Binding	Microtubule Motor Activity ATP Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Double-strand Break Repair Via Break-induced Replication Inner Cell Mass Cell Proliferation DNA Strand Elongation Involved In DNA Replication	Formation Of Primary Germ Layer Regulation Of Receptor Recycling Golgi To Endosome Transport Microtubule-based Movement Epidermal Growth Factor Receptor Signaling Pathway Endoderm Development Fibroblast Growth Factor Receptor Signaling Pathway Receptor Catabolic Process Early Endosome To Late Endosome Transport
Pathways		Unwinding of DNA Unwinding of DNA	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS			Adult body size ( 32376654) Adventurousness ( 30643258) Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Asthma ( 27611488) Body mass index ( 26426971) Chronotype ( 30696823) Dimensional psychopathology (Positive) ( 29496196) Emphysema imaging phenotypes ( 26030696) Gut microbiota alpha diversity (Chao1 index) ( 33208821) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota alpha diversity (Shannon index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) Ileal carcinoids ( 21139019) Intelligence ( 22449649) Lipid traits ( 30576415) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Sweet taste preference ( 32572145)
Interacting Genes		17 interacting genes: BIN3 CDC45 CTNNBIP1 DMAP1 GINS1 GINS2 GINS3 KIF16B LHX8 MCM2 PBX4 POLA1 POLD1 POLE PPP1R13B SIK1 SIK1B	10 interacting genes: GABARAPL2 GINS4 IL16 ITSN1 LGALS3 PRKAA1 PRKAA2 SMYD1 TCEANC TSR2
Entrez ID		84296	55614
HPRD ID		11583	10731
Ensembl ID		ENSG00000147536	ENSG00000089177
Uniprot IDs		Q9BRT9	A0A140VK74 A0A1B0GTU3 Q96L93
PDB IDs		2E9X 2EHO 2Q9Q 6XTX 6XTY	2V14 6EE0
Enriched GO Terms of Interacting Partners?
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