ASCC2 and RNF11

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	RNF11
Description		activating signal cointegrator 1 complex subunit 2	ring finger protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Binding	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways		ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350
Entrez ID		84164	26994
HPRD ID		16515	09955
Ensembl ID		ENSG00000100325	ENSG00000123091
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	Q9Y3C5
PDB IDs		2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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