ASCC2 and GNL3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	GNL3
Description		activating signal cointegrator 1 complex subunit 2	G protein nucleolar 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Extracellular Space Nucleus Chromosome Nucleolus Membrane Nuclear Body Midbody
	Molecular Function	Protein Binding Ubiquitin Binding	RNA Binding Protein Binding GTP Binding MRNA 5'-UTR Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated	Cell Population Proliferation Stem Cell Division Stem Cell Population Maintenance Positive Regulation Of Telomere Maintenance Positive Regulation Of Protein Sumoylation Regulation Of Cell Population Proliferation Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Positive Regulation Of Protein Localization To Chromosome, Telomeric Region
Pathways		ALKBH3 mediated reversal of alkylation damage	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Adiponectin levels ( 22479202) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Bipolar disorder ( 21926972 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Intelligence (MTAG) ( 29326435) Osteoarthritis ( 22763110) Schizophrenia ( 28991256 25056061 29483656 23974872) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	9 interacting genes: ASCC2 CEP19 DYSF MDM2 NPM1 PPP2R5A PTEN STAT3 TP53
Entrez ID		84164	26354
HPRD ID		16515	06419
Ensembl ID		ENSG00000100325	ENSG00000163938
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	Q9BVP2
PDB IDs		2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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