ASCC2 and CUTC

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	CUTC
Description		activating signal cointegrator 1 complex subunit 2	cutC copper transporter
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Protein Binding Ubiquitin Binding	Copper Ion Binding Protein Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated	Copper Ion Transport Protein Tetramerization Copper Ion Homeostasis
Pathways		ALKBH3 mediated reversal of alkylation damage	Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Colorectal cancer ( 26151821) Crohn's disease ( 22412388) Obesity-related traits ( 23251661)
Interacting Genes		41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	18 interacting genes: ASCC2 ATXN1 BCL6 CDC37 CEP76 KANK2 LNX1 MEOX2 MESD NADSYN1 NIF3L1 NTAQ1 NUDT18 PICK1 PIM2 SDCBP SLC27A6 SPG21
Entrez ID		84164	51076
HPRD ID		16515	13100
Ensembl ID		ENSG00000100325	ENSG00000119929
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	Q9NTM9
PDB IDs		2DI0 6YXQ	3IWP
Enriched GO Terms of Interacting Partners?
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