PRAM1 and SKAP2

Data Source:
HPRD (in vivo)

		PRAM1	SKAP2
Description		PML-RARA regulated adaptor molecule 1	src kinase associated phosphoprotein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Protein-containing Complex	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Lipid Binding Protein Kinase Binding	Protein Binding
	Biological Process	Integrin-mediated Signaling Pathway Regulation Of Neutrophil Degranulation T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane	Signal Transduction Negative Regulation Of Cell Population Proliferation B Cell Activation Protein-containing Complex Assembly
Pathways			Signal regulatory protein family interactions
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Coronary artery disease ( 29212778) Height ( 18391951)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic venous disease ( 28374850) Disease free survival in colon cancer ( 31811950) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Macular thickness ( 30535121) Monocyte count ( 32888494) Peak expiratory flow ( 30804560) Small cell lung carcinoma ( 28604730) Survival in colon cancer ( 31811950) Systemic lupus erythematosus ( 28714469)
Interacting Genes		25 interacting genes: A2M ABI2 APOE APP BCAR1 CCDC57 CDC37 FXR1 FXR2 GOLGA2 KRT40 LCP2 LYN MAST1 MXD1 NEDD9 NEK6 PSEN1 RNF32 SH3RF1 SKAP1 SKAP2 TP53BP2 TRIM27 UBE2E2	20 interacting genes: APP BLK DNAJB6 FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1
Entrez ID		84106	8935
HPRD ID		05926	05558
Ensembl ID		ENSG00000133246	ENSG00000005020
Uniprot IDs		Q96QH2	B7Z5R3 O75563
PDB IDs			3OMH
Enriched GO Terms of Interacting Partners?
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