TAGLN2 and EHD2

Data Source:
BioGRID (two hybrid)

		TAGLN2	EHD2
Description		transgelin 2	EH domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Vesicle Extracellular Exosome	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Microtubule Cytoskeleton Extrinsic Component Of Membrane Endocytic Vesicle Intracellular Membrane-bounded Organelle Intercellular Bridge Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Cadherin Binding	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Platelet Degranulation Epithelial Cell Differentiation	Endocytosis Blood Coagulation Endosomal Transport Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways		Platelet degranulation	Factors involved in megakaryocyte development and platelet production
Drugs		Artenimol
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease-related phenotypes ( 25557950) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: APP EHD2 SUMO2	14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23
Entrez ID		8407	30846
HPRD ID		06864	10434
Ensembl ID		ENSG00000158710	ENSG00000024422
Uniprot IDs		A0A384MTL2 P37802	A0A024R0S6 Q9NZN4
PDB IDs		1WYM
Enriched GO Terms of Interacting Partners?
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