PLEKHN1 and PDLIM7

Data Source:
BioGRID (two hybrid)

		PLEKHN1	PDLIM7
Description		pleckstrin homology domain containing N1	PDZ and LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization	Ossification Receptor-mediated Endocytosis Axon Guidance Heart Development Actin Cytoskeleton Organization Positive Regulation Of Osteoblast Differentiation Muscle Structure Development
Pathways			RET signaling
Drugs
Diseases
GWAS		Height ( 31562340) Parkinson's disease ( 26227905)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		44 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CALCOCO2 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PPP1R32 PRICKLE4 PRKAA2 PXN REL RFX6 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1	62 interacting genes: ABI2 AP5B1 BAG3 BSG CATSPER1 CCDC185 DDX6 DGCR6 DNER ENKD1 FAM214B FAM71C FAM90A1 FNDC11 FRS3 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		84069	9260
HPRD ID		13190	10436
Ensembl ID		ENSG00000187583	ENSG00000196923
Uniprot IDs		Q494U1	Q9NR12
PDB IDs			2Q3G
Enriched GO Terms of Interacting Partners?
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