PLEKHN1 and KRT83

Data Source:
BioGRID (two hybrid)

		PLEKHN1	KRT83
Description		pleckstrin homology domain containing N1	keratin 83
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane	Extracellular Space Cytosol Keratin Filament
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding	Protein Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization	Aging Epidermis Development Keratinization Hair Cycle Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS		Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		44 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CALCOCO2 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PPP1R32 PRICKLE4 PRKAA2 PXN REL RFX6 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1	40 interacting genes: ADAM12 ANKS1A C11orf87 CEP57 CREB5 CYSRT1 GEM GNE GSTP1 HOXA1 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT38 KRT39 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-3 KRTAP3-3 KRTAP6-2 MEOX2 NBPF19 NOTCH2NLA NRF1 OIP5 PITX1 PLEKHN1 POU4F2 ZDHHC1
Entrez ID		84069	3889
HPRD ID		13190	09097
Ensembl ID		ENSG00000187583	ENSG00000170523
Uniprot IDs		Q494U1	P78385
PDB IDs
Enriched GO Terms of Interacting Partners?
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