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PLEKHN1 and SORBS3
Data Source:
BioGRID
(two hybrid)
PLEKHN1
SORBS3
Description
pleckstrin homology domain containing N1
sorbin and SH3 domain containing 3
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Cytoskeleton
Plasma Membrane
Mitochondrial Membrane
Nucleus
Cytosol
Cytoskeleton
Focal Adhesion
Molecular Function
Phosphatidylserine Binding
Protein Binding
Phosphatidic Acid Binding
Cardiolipin Binding
Phosphatidylinositol Phosphate Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Transcription Factor Binding
Vinculin Binding
Biological Process
Response To Hypoxia
Positive Regulation Of Apoptotic Process
3'-UTR-mediated MRNA Destabilization
Negative Regulation Of Transcription By RNA Polymerase II
Muscle Contraction
Actin Filament Organization
Cell Adhesion
Cell-substrate Adhesion
Positive Regulation Of MAPK Cascade
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Stress Fiber Assembly
Pathways
Smooth Muscle Contraction
Drugs
Diseases
GWAS
Height (
31562340
)
Parkinson's disease (
26227905
)
Diastolic blood pressure (
30224653
)
HIV-1 viral setpoint (
20205591
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Parkinson's disease (
28892059
)
Interacting Genes
44 interacting genes:
ABI2
AKAP8L
ARID5A
ATXN1
CALCOCO2
CBY2
CYSRT1
FHL5
HOXA1
KRT31
KRT36
KRT83
KRTAP1-3
KRTAP19-6
KRTAP6-2
LPXN
LZTS2
MTUS2
NBPF19
NFKBID
NOTCH2NLA
PDLIM7
PIH1D1
PPM1J
PPP1R16B
PPP1R32
PRICKLE4
PRKAA2
PXN
REL
RFX6
SORBS3
SSC4D
TAX1BP1
TCF4
TP53BP2
TRAF1
TRIM27
TRIP6
USP54
WWOX
ZC4H2
ZNF438
ZRANB1
133 interacting genes:
ABI2
ABL1
ADAM15
ADAMTSL4
ADAT3
AKIRIN2
AKT2
ANKS1A
ARNT2
C1orf109
CATSPER1
CBFA2T2
CBLB
CCDC102B
CCDC120
CCDC187
CCDC57
CCDC6
CCHCR1
CCNH
CCNL1
CDC23
CDKN2C
CFAP206
CHERP
COG4
CPEB2
CPNE1
CPNE2
CPNE8
CPSF7
CRACR2A
DDX17
DDX6
DIP2A
DLG5
DMRTB1
DVL2
DVL3
EFHC1
EFS
EIF3H
ENKD1
FAM214B
FAM53C
FASLG
FBXL19
FLOT1
FNDC11
GAS8
GEM
GLRA1
GPANK1
GPKOW
GYS1
HGS
HNRNPF
HNRNPK
HNRNPUL1
IMP3
INPPL1
INSC
IQUB
KANK2
KIAA0408
KIAA1217
KIFC3
MAPK1
MAPK3
MKRN3
MYO15B
NAB2
NAF1
NCK1
NCKIPSD
NEK6
NFKBID
NHSL2
NOTCH3
NRBP1
OIP5
OSGIN1
PAK2
PAK5
PHETA1
PHF1
PIBF1
PLEKHN1
PLOD3
PNMA5
POLE2
POLR1C
PPFIA3
PPIL6
PPP1R18
QARS1
RAD51D
RBMX
RIN1
ROPN1
RUNX1T1
SAFB2
SAXO1
SCNM1
SETD5
SH2D4A
SOCS7
SPG21
SRCIN1
SYNPO2L
TBC1D22B
TCEANC
TEAD4
TEPSIN
TNS2
TRIM23
TRIM27
TRIM41
TSGA10
TSGA10IP
TXLNA
USP2
VARS2
VCL
VPS37B
VPS37C
WIPF2
ZBED1
ZBTB25
ZBTB7B
ZC2HC1C
ZC4H2
ZNF414
Entrez ID
84069
10174
HPRD ID
13190
11535
Ensembl ID
ENSG00000187583
ENSG00000120896
Uniprot IDs
Q494U1
O60504
PDB IDs
2CT3
2DLM
2NWM
2YUP
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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