PLEKHN1 and KRT36

Data Source:
BioGRID (two hybrid)

		PLEKHN1	KRT36
Description		pleckstrin homology domain containing N1	keratin 36
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytoskeleton Plasma Membrane Mitochondrial Membrane	Cytosol Intermediate Filament Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding	Structural Constituent Of Skin Epidermis
	Biological Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization	Biological_process Keratinization Regulation Of Keratinocyte Differentiation Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		44 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CALCOCO2 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PPP1R32 PRICKLE4 PRKAA2 PXN REL RFX6 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1	52 interacting genes: ABI2 ABI3 AIMP2 AMOT APP BCAS2 C1orf216 CCBE1 CCHCR1 CDC23 DMRT3 EXOC8 GEM GPS2 HCK HGS HOXC8 KRT1 KRT2 KRT3 KRT4 KRT6A KRT6C KRT73 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT85 KRT86 MAP3K1 MYOZ1 MYOZ3 PKN1 PLEKHN1 PPP1R18 PSMB1 QARS1 RESF1 RIBC1 SMURF1 TMSB4X TRAF4 TSGA10IP TTC23 TTLL10 TXLNA ZNF414 ZNF785
Entrez ID		84069	8689
HPRD ID		13190	05174
Ensembl ID		ENSG00000187583	ENSG00000126337
Uniprot IDs		Q494U1	O76013
PDB IDs
Enriched GO Terms of Interacting Partners?
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