CFD

Description		complement factor D
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GO Annotations	Cellular Component	Extracellular Region Platelet Alpha Granule Lumen Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Platelet Degranulation Proteolysis Complement Activation Complement Activation, Alternative Pathway Notch Signaling Pathway Neutrophil Degranulation
Pathways		Platelet degranulation Alternative complement activation Neutrophil degranulation
Drugs		2-Aminobenzyl alcohol 3,4-Dichloroisocoumarin
Diseases		Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		2 interacting genes: HDHD2 SERPINF2
Entrez ID		1675
HPRD ID		00600
Ensembl ID		ENSG00000197766
Uniprot IDs		A6XNE2 K7ERG9 P00746
PDB IDs		1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XW9 2XWA 2XWB 4CBN 4CBO 4D9R 5FBE 5FBI 5FCK 5MT0 5MT4 5NAR 5NAT 5NAW 5NB6 5NB7 5NBA 5TCA 5TCC 6FTY 6FTZ 6FUG 6FUH 6FUI 6FUJ 6FUT 6QMR 6QMT
Enriched GO Terms of Interacting Partners?
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