Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
PIP5K1A and MIR140
Data Source:
BioGRID
(unspecified method)
PIP5K1A
MIR140
Description
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
microRNA 140
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
MRNA Cleavage And Polyadenylation Specificity Factor Complex
Plasma Membrane
Focal Adhesion
Nuclear Speck
Lamellipodium
Ruffle Membrane
Extracellular Space
Molecular Function
Protein Binding
ATP Binding
1-phosphatidylinositol-4-phosphate 5-kinase Activity
Kinase Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Glycerophospholipid Metabolic Process
Phosphatidylinositol Biosynthetic Process
Phagocytosis
Signal Transduction
Phospholipid Biosynthetic Process
Fibroblast Migration
Regulation Of Phosphatidylinositol 3-kinase Signaling
Cell Migration
Keratinocyte Differentiation
Actin Cytoskeleton Reorganization
Phosphatidylinositol Phosphorylation
Focal Adhesion Assembly
Cell Chemotaxis
Protein Localization To Plasma Membrane
Activation Of GTPase Activity
Ruffle Assembly
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of BMP Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Gene Silencing By MiRNA
Defense Response To Bacterium
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Production
Cellular Response To Amyloid-beta
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching
Pathways
Synthesis of PIPs at the plasma membrane
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Body mass index (
26426971
)
Interacting Genes
16 interacting genes:
APP
ARF1
ARF5
ARF6
BTK
CADPS
CASP3
KRAS
MIR140
MIR34B
NEDD4
PIP5KL1
PLD1
PLD2
RHOU
TEC
68 interacting genes:
ADARB1
AIMP1
APOBEC3B
C1QBP
CELF1
CELF2
CRTAP
CSTF1
DARS1
DDX1
DDX21
DDX3X
DDX49
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
NOL6
NONO
NUDT21
PDCD11
PIKFYVE
PIP5K1A
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM14
RTCB
SF3B1
SF3B3
SFPQ
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
UTP20
YBX1
YBX3
Entrez ID
8394
406932
HPRD ID
04470
Ensembl ID
ENSG00000143398
ENSG00000208017
Uniprot IDs
A6PW57
Q99755
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?