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MIR140 and EPRS1
Data Source:
BioGRID
(unspecified method)
MIR140
EPRS1
Description
microRNA 140
glutamyl-prolyl-tRNA synthetase 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
GAIT Complex
Ribonucleoprotein Complex
Molecular Function
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Glutamate-tRNA Ligase Activity
Proline-tRNA Ligase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
GTPase Binding
Biological Process
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of BMP Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Gene Silencing By MiRNA
Defense Response To Bacterium
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Production
Cellular Response To Amyloid-beta
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching
TRNA Aminoacylation For Protein Translation
Glutamyl-tRNA Aminoacylation
Prolyl-tRNA Aminoacylation
Negative Regulation Of Translation
Cellular Response To Insulin Stimulus
Protein-containing Complex Assembly
Cellular Response To Interferon-gamma
Regulation Of Long-chain Fatty Acid Import Into Cell
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
tRNA modification in the nucleus and cytosol
Drugs
Glutamic acid
Proline
5'-O-(L-Prolylsulfamoyl)adenosine
5'-O-(L-Cysteinylsulfamoyl)adenosine
5'-O-(N-(Alanyl)sulfamoyl)adenosine
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
68 interacting genes:
ADARB1
AIMP1
APOBEC3B
C1QBP
CELF1
CELF2
CRTAP
CSTF1
DARS1
DDX1
DDX21
DDX3X
DDX49
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
NOL6
NONO
NUDT21
PDCD11
PIKFYVE
PIP5K1A
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM14
RTCB
SF3B1
SF3B3
SFPQ
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
UTP20
YBX1
YBX3
89 interacting genes:
AIMP2
ARL4D
CDC42
DUS2
DUX4
EEF1D
ESR1
HSP90AA1
IARS1
LINC01554
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NELFCD
PTEN
RARS1
SUMO2
SYNCRIP
TAB1
Entrez ID
406932
2058
HPRD ID
00703
Ensembl ID
ENSG00000208017
ENSG00000136628
Uniprot IDs
P07814
PDB IDs
1FYJ
4HVC
4K86
4K87
4K88
5A1N
5A34
5A5H
5BMU
5V58
5VAD
5Y6L
6IY6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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