RAB34 and CA8

Data Source:
BioGRID (two hybrid)

		RAB34	CA8
Description		RAB34, member RAS oncogene family	carbonic anhydrase 8
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Golgi Stack Cilium Phagocytic Vesicle Membrane Vesicle Golgi Cisterna Ruffle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Small GTPase Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Endocytosis Antigen Processing And Presentation Cell Projection Organization Lysosome Localization Golgi To Plasma Membrane Protein Transport Macropinocytosis Positive Regulation Of Smoothened Signaling Pathway Protein Localization To Plasma Membrane Phagosome Maturation Phagosome-lysosome Fusion	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling
Pathways		RAB geranylgeranylation
Drugs			Zonisamide
Diseases
GWAS		Urate levels in lean individuals ( 25811787)	Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		8 interacting genes: CA8 RABGAP1L RALA RILP SMAD1 SMAD2 SMAD4 TGFBR1	14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3
Entrez ID		83871	767
HPRD ID		06701	00266
Ensembl ID		ENSG00000109113	ENSG00000178538
Uniprot IDs		A0A024QZ68 B4DNC0 E7ES60 P0DI83 Q96PJ7 Q9BZG1	P35219
PDB IDs			2W2J
Enriched GO Terms of Interacting Partners?
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