CA8 and RAB34

Data Source:
BioGRID (two hybrid)

		CA8	RAB34
Description		carbonic anhydrase 8	RAB34, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Golgi Apparatus Golgi Stack Cilium Phagocytic Vesicle Membrane Vesicle Golgi Cisterna Ruffle Membrane Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Small GTPase Binding
	Biological Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling	Endocytosis Antigen Processing And Presentation Cell Projection Organization Lysosome Localization Golgi To Plasma Membrane Protein Transport Macropinocytosis Positive Regulation Of Smoothened Signaling Pathway Protein Localization To Plasma Membrane Phagosome Maturation Phagosome-lysosome Fusion
Pathways			RAB geranylgeranylation
Drugs		Zonisamide
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Urate levels in lean individuals ( 25811787)
Interacting Genes		14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3	8 interacting genes: CA8 RABGAP1L RALA RILP SMAD1 SMAD2 SMAD4 TGFBR1
Entrez ID		767	83871
HPRD ID		00266	06701
Ensembl ID		ENSG00000178538	ENSG00000109113
Uniprot IDs		P35219	A0A024QZ68 B4DNC0 E7ES60 P0DI83 Q96PJ7 Q9BZG1
PDB IDs		2W2J
Enriched GO Terms of Interacting Partners?
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