CA8 and LRCH4

		CA8	LRCH4
Description		carbonic anhydrase 8	leucine rich repeats and calponin homology domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	PML Body
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity	Protein Binding
	Biological Process	One-carbon Metabolic Process Phosphatidylinositol-mediated Signaling	Nervous System Development
Pathways
Drugs		Zonisamide
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 30072576) Cardiac hypertrophy ( 21348951) Free thyroxine concentration ( 30367059) Height ( 31562340) Hemoglobin ( 32888494) Myopia ( 27182965) Obesity-related traits ( 23251661) Parkinson's disease ( 27182965) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to amphetamines ( 22952603) Schizophrenia ( 28991256 25056061 29483656 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Brain morphology (MOSTest) ( 32665545) Macular thickness ( 30535121) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		14 interacting genes: CRX GGA2 HSD17B14 INTS7 ITPR1 KLHL8 LMNB2 LNX1 LRCH4 MAGED1 RAB34 SPDL1 STAT3 TBX3	16 interacting genes: CA8 CYB5R3 ELOVL7 HSD17B11 KASH5 KRT40 KRTAP10-7 KRTAP10-8 MDFI NOTCH2NLA RBBP6 RETREG3 RNASEK RTN4 SIN3A SPOP
Entrez ID		767	4034
HPRD ID		00266	10062
Ensembl ID		ENSG00000178538	ENSG00000077454
Uniprot IDs		P35219	O75427
PDB IDs		2W2J
Enriched GO Terms of Interacting Partners?
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