IGFBP2 and INO80B

Data Source:
BioGRID (pull down, affinity chromatography technology)

		IGFBP2	INO80B
Description		insulin like growth factor binding protein 2	INO80 complex subunit B
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Apical Plasma Membrane Cytoplasmic Vesicle Extracellular Exosome	Nucleoplasm Nucleolus Ino80 Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Insulin-like Growth Factor I Binding Insulin-like Growth Factor II Binding	Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Female Pregnancy Aging Response To Nutrient Response To Mechanical Stimulus Response To Lithium Ion Response To Estradiol Response To Retinoic Acid Cellular Response To Hormone Stimulus Regulation Of Growth Positive Regulation Of Activated T Cell Proliferation Response To Drug Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Response To Estrogen Cellular Protein Metabolic Process Response To Glucocorticoid Negative Regulation Of Canonical Wnt Signaling Pathway	DNA Repair DNA Recombination Protein Deubiquitination ATP-dependent Chromatin Remodeling
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Glomerular filtration rate (creatinine) ( 28452372) Gut microbiota alpha diversity (Chao1 index) ( 33208821) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) Mitral valve prolapse ( 26301497) Thyroid stimulating hormone levels ( 25743335) Type 2 diabetes ( 26818947)
Interacting Genes		6 interacting genes: GSDMB IGF1 IGF2 INO80B KLK2 TF	64 interacting genes: ABI2 BANP BHLHB9 BOLL CARD9 CAVIN1 CCDC85B CD81 CDR2L CEP70 CSNK2B CYSRT1 DPPA4 DVL3 E2F6 FLACC1 GOLGA6L9 HMBOX1 HMGXB4 HOMEZ HOXA1 HSF2BP IGFBP2 KCTD7 KRT34 KRT40 KRTAP10-8 KRTAP12-2 KRTAP19-1 KRTAP6-2 LHX4 LIMS1 LZTS2 MID2 MKRN3 MORN3 MTUS2 MYLIP NBPF19 NOTCH2NLA PICK1 PIP4K2B PLAGL2 PNMA1 PNMA2 RBM39 RIMBP3C SOX13 SSX2IP STAC3 THAP1 TLE5 TNS2 TRAF2 TRIB3 TRIM27 TSPYL2 U2AF2 UIMC1 USH1G YAF2 ZNF526 ZNF552 ZRANB1
Entrez ID		3485	83444
HPRD ID		00898	17110
Ensembl ID		ENSG00000115457	ENSG00000115274
Uniprot IDs		C9JMY1 P18065	Q9C086
PDB IDs		2H7T	6HTS
Enriched GO Terms of Interacting Partners?
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