SF3B5 and TRAPPC6A

Data Source:
BioGRID (two hybrid)

		SF3B5	TRAPPC6A
Description		splicing factor 3b subunit 5	trafficking protein particle complex subunit 6A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U2 SnRNP U12-type Spliceosomal Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	RNA Binding Protein Binding Splicing Factor Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS			Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		6 interacting genes: MIR21 MIRLET7G SF3B6 STAMBPL1 TRAPPC6A U2AF2	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		83443	79090
HPRD ID		18042	14503
Ensembl ID		ENSG00000169976	ENSG00000007255
Uniprot IDs		Q9BWJ5	B7TZ90 O75865
PDB IDs		5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9 6Y50 6Y5Q	2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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