FZD7 and NCALD

Data Source:
BioGRID (two hybrid)

		FZD7	NCALD
Description		frizzled class receptor 7	neurocalcin delta
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Cytosol Clathrin Coat Of Trans-Golgi Network Vesicle
	Molecular Function	G Protein-coupled Receptor Activity Frizzled Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity	Actin Binding Calcium Ion Binding Protein Binding Tubulin Binding Clathrin Binding
	Biological Process	Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell-substrate Adhesion Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Stem Cell Population Maintenance Neuron Differentiation T Cell Differentiation In Thymus Substrate Adhesion-dependent Cell Spreading Non-canonical Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Phosphorylation Negative Regulation Of Ectodermal Cell Fate Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JNK Cascade Somatic Stem Cell Division Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Mesenchymal To Epithelial Transition Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Retinoic Acid Negative Regulation Of Cardiac Muscle Cell Differentiation	Vesicle-mediated Transport
Pathways		Class B/2 (Secretin family receptors) PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping	Activation of Ca-permeable Kainate Receptor
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Blond vs. brown/black hair color ( 30531825) Heel bone mineral density ( 30598549 28869591) Metabolite levels ( 23823483) Risk-taking tendency (4-domain principal component model) ( 30643258) Total body bone mineral density ( 29304378)	Age-related hearing impairment ( 24939585) Cerebral amyloid angiopathy ( 25188341) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Coffee consumption ( 21876539) Cognitive performance ( 20125193) Coronary artery disease ( 33020668) Gait speed in old age ( 28077804) LDL peak particle diameter (total fat intake interaction) ( 26112879) Medication use (beta blocking agents) ( 31015401) Microalbuminuria ( 26631737) Perceived sweetness of sucrose ( 31005972) Red cell distribution width ( 32888494) Systolic blood pressure ( 30224653)
Interacting Genes		28 interacting genes: ADCY1 AIG1 AQP9 BCL2L13 CLN8 CLPTM1 DLG1 DLG2 DLG4 FFAR2 GNAS HPCAL1 LEUTX MAGI3 MGST1 NCALD NCS1 PDAP1 PRNP PSME3IP1 SGTA SGTB SLC30A4 SLC35B1 TMEM237 UBQLN1 UBQLN2 UBQLN4	33 interacting genes: ACTB ANOS1 APOL3 C19orf44 C1QTNF2 CLTC CREM DTX2 FGF6 FZD7 GOLGA7 GPX7 IGFBP6 KRT6A LCE2D LIF LITAF LY6G6D MEOX2 MICOS10-NBL1 MIEF2 MLLT10 MYDGF NBL1 PLAAT2 PNP SBSN SPRED1 SRGN TMEM14B TPSG1 TUBA4A TUBB
Entrez ID		8324	83988
HPRD ID		04560	09466
Ensembl ID		ENSG00000155760	ENSG00000104490
Uniprot IDs		O75084	B2RB70 P61601
PDB IDs		4Z33 5T44 5URV 5WBS 6NE2 6NE4 6O3A 6O3B
Enriched GO Terms of Interacting Partners?
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