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FZD7 and SLC35B1
Data Source:
BioGRID
(two hybrid)
FZD7
SLC35B1
Description
frizzled class receptor 7
solute carrier family 35 member B1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Recycling Endosome Membrane
Integral Component Of Golgi Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
G Protein-coupled Receptor Activity
Frizzled Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Wnt-protein Binding
PDZ Domain Binding
Wnt-activated Receptor Activity
UDP-galactose Transmembrane Transporter Activity
UDP-glucose Transmembrane Transporter Activity
Protein Binding
Transmembrane Transporter Activity
Biological Process
Regulation Of Transcription, DNA-templated
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Cell-substrate Adhesion
Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration
Stem Cell Population Maintenance
Neuron Differentiation
T Cell Differentiation In Thymus
Substrate Adhesion-dependent Cell Spreading
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Positive Regulation Of Phosphorylation
Negative Regulation Of Ectodermal Cell Fate Specification
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of JNK Cascade
Somatic Stem Cell Division
Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Mesenchymal To Epithelial Transition
Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Retinoic Acid
Negative Regulation Of Cardiac Muscle Cell Differentiation
Carbohydrate Transport
UDP-glucose Transmembrane Transport
UDP-galactose Transmembrane Transport
Pathways
Class B/2 (Secretin family receptors)
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Blond vs. brown/black hair color (
30531825
)
Heel bone mineral density (
30598549
28869591
)
Metabolite levels (
23823483
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Total body bone mineral density (
29304378
)
Interacting Genes
28 interacting genes:
ADCY1
AIG1
AQP9
BCL2L13
CLN8
CLPTM1
DLG1
DLG2
DLG4
FFAR2
GNAS
HPCAL1
LEUTX
MAGI3
MGST1
NCALD
NCS1
PDAP1
PRNP
PSME3IP1
SGTA
SGTB
SLC30A4
SLC35B1
TMEM237
UBQLN1
UBQLN2
UBQLN4
20 interacting genes:
APP
AQP6
ARL13B
BNIP3
CCDC107
CD74
CD79A
CREB3L1
DRD2
FKBP8
FXYD3
FZD5
FZD7
GPR152
HRH1
MFF
PDZK1IP1
PTPN5
VAPA
VSIR
Entrez ID
8324
10237
HPRD ID
04560
10237
Ensembl ID
ENSG00000155760
ENSG00000121073
Uniprot IDs
O75084
D3DTX1
P78383
PDB IDs
4Z33
5T44
5URV
5WBS
6NE2
6NE4
6O3A
6O3B
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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