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FZD7 and TMEM237
Data Source:
BioGRID
(two hybrid)
FZD7
TMEM237
Description
frizzled class receptor 7
transmembrane protein 237
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Recycling Endosome Membrane
Membrane
Integral Component Of Membrane
Photoreceptor Connecting Cilium
Ciliary Transition Zone
Cone Photoreceptor Outer Segment
Rod Photoreceptor Outer Segment
Molecular Function
G Protein-coupled Receptor Activity
Frizzled Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Wnt-protein Binding
PDZ Domain Binding
Wnt-activated Receptor Activity
Protein Binding
Biological Process
Regulation Of Transcription, DNA-templated
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Cell-substrate Adhesion
Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration
Stem Cell Population Maintenance
Neuron Differentiation
T Cell Differentiation In Thymus
Substrate Adhesion-dependent Cell Spreading
Non-canonical Wnt Signaling Pathway
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Positive Regulation Of Phosphorylation
Negative Regulation Of Ectodermal Cell Fate Specification
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of JNK Cascade
Somatic Stem Cell Division
Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Mesenchymal To Epithelial Transition
Regulation Of Canonical Wnt Signaling Pathway
Cellular Response To Retinoic Acid
Negative Regulation Of Cardiac Muscle Cell Differentiation
Regulation Of Wnt Signaling Pathway
Cilium Assembly
Pathways
Class B/2 (Secretin family receptors)
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Blond vs. brown/black hair color (
30531825
)
Heel bone mineral density (
30598549
28869591
)
Metabolite levels (
23823483
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Total body bone mineral density (
29304378
)
Lung cancer (
28604730
)
Lung cancer in ever smokers (
28604730
)
Interacting Genes
28 interacting genes:
ADCY1
AIG1
AQP9
BCL2L13
CLN8
CLPTM1
DLG1
DLG2
DLG4
FFAR2
GNAS
HPCAL1
LEUTX
MAGI3
MGST1
NCALD
NCS1
PDAP1
PRNP
PSME3IP1
SGTA
SGTB
SLC30A4
SLC35B1
TMEM237
UBQLN1
UBQLN2
UBQLN4
122 interacting genes:
ABHD16A
ADAM33
ADIPOQ
APOD
APOL3
AQP1
ATP13A1
BET1
BLCAP
BNIP2
BTN2A2
C1GALT1
C3orf52
C4orf3
CBLIF
CCDC167
CD53
CDS1
CFHR5
CLDN4
CLN6
CNIH3
CTSA
CXCL16
CXCL9
CYB5B
EFNA5
EMC6
ERMP1
EXTL1
FBXO7
FKBP14
FXYD6
FZD7
GJB2
GKN2
GPR152
GPR25
GPR42
GRM2
GUCA2A
GYPA
IER3IP1
IFNGR1
IGFBP5
INSIG1
INSIG2
JAGN1
LAT
LEPROTL1
LPAR3
LRP10
LTA
MFF
MFSD5
MFSD6
MS4A13
OPRD1
ORMDL3
OTOP2
OTOP3
PLPPR2
PNLIPRP1
POMGNT1
PRB1
PRNP
RETREG3
RHD
ROBO2
RPRM
RUSF1
SEC22A
SERP2
SERPINE1
SFXN5
SLC12A7
SLC16A4
SLC29A2
SLC2A5
SLC30A8
SLC35A4
SLC35B2
SLC35B4
SLC35E4
SLC35G1
SLC38A2
SLC38A7
SLC39A2
SLC39A9
SLC41A1
SLC41A2
SLC52A1
SLC5A4
SLC7A1
SLC7A3
ST6GAL2
STRIT1
STX8
TLCD4
TM4SF19
TM6SF2
TMEFF2
TMEM107
TMEM11
TMEM128
TMEM144
TMEM147
TMEM179B
TMEM201
TMEM254
TMEM42
TMEM60
TMEM72
TMEM86B
TRARG1
UNC93A
UNC93B1
UPK1B
VAMP3
VEGFA
YIPF6
ZFPL1
Entrez ID
8324
65062
HPRD ID
04560
12448
Ensembl ID
ENSG00000155760
ENSG00000155755
Uniprot IDs
O75084
Q96Q45
PDB IDs
4Z33
5T44
5URV
5WBS
6NE2
6NE4
6O3A
6O3B
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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