FZD7 and PSME3IP1

Data Source:
BioGRID (two hybrid)

		FZD7	PSME3IP1
Description		frizzled class receptor 7	proteasome activator subunit 3 interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Nucleus
	Molecular Function	G Protein-coupled Receptor Activity Frizzled Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell-substrate Adhesion Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Stem Cell Population Maintenance Neuron Differentiation T Cell Differentiation In Thymus Substrate Adhesion-dependent Cell Spreading Non-canonical Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Phosphorylation Negative Regulation Of Ectodermal Cell Fate Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JNK Cascade Somatic Stem Cell Division Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Mesenchymal To Epithelial Transition Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Retinoic Acid Negative Regulation Of Cardiac Muscle Cell Differentiation	Negative Regulation Of Protein Binding Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		Class B/2 (Secretin family receptors) PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Blond vs. brown/black hair color ( 30531825) Heel bone mineral density ( 30598549 28869591) Metabolite levels ( 23823483) Risk-taking tendency (4-domain principal component model) ( 30643258) Total body bone mineral density ( 29304378)
Interacting Genes		28 interacting genes: ADCY1 AIG1 AQP9 BCL2L13 CLN8 CLPTM1 DLG1 DLG2 DLG4 FFAR2 GNAS HPCAL1 LEUTX MAGI3 MGST1 NCALD NCS1 PDAP1 PRNP PSME3IP1 SGTA SGTB SLC30A4 SLC35B1 TMEM237 UBQLN1 UBQLN2 UBQLN4	7 interacting genes: ATP13A2 CSNK2A1 FZD7 LRRK2 MFHAS1 MTNR1B TRAF2
Entrez ID		8324	80011
HPRD ID		04560	11389
Ensembl ID		ENSG00000155760	ENSG00000172775
Uniprot IDs		O75084	A0A024R6T8 Q9GZU8
PDB IDs		4Z33 5T44 5URV 5WBS 6NE2 6NE4 6O3A 6O3B
Enriched GO Terms of Interacting Partners?
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