F8A1 and SNTA1

Data Source:
BioGRID (unspecified method)

		F8A1	SNTA1
Description		coagulation factor VIII associated 1	syntrophin alpha 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Early Endosome Nuclear Body	Intracellular Anatomical Structure Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Synapse Postsynaptic Membrane
	Molecular Function	Molecular_function Protein Binding	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding
	Biological Process	Vesicle Cytoskeletal Trafficking Negative Regulation Of Proteasomal Protein Catabolic Process	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport
Pathways
Drugs
Diseases			Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS			HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)
Interacting Genes		6 interacting genes: DNMT3A HTT MTNR1A SH3GLB1 SNTA1 TLR10	74 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6
Entrez ID		8263	6640
HPRD ID		02374	03009
Ensembl ID		ENSG00000277203	ENSG00000101400
Uniprot IDs		P23610	Q13424
PDB IDs		6EZ8 6X9O
Enriched GO Terms of Interacting Partners?
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