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SNTA1 and HTR2C
Data Source:
BioGRID
(unspecified method)
SNTA1
HTR2C
Description
syntrophin alpha 1
5-hydroxytryptamine receptor 2C
Image
No pdb structure
GO Annotations
Cellular Component
Intracellular Anatomical Structure
Cytoplasm
Cytoskeleton
Dystrophin-associated Glycoprotein Complex
Syntrophin Complex
Lateral Plasma Membrane
Neuromuscular Junction
Protein-containing Complex
Sarcolemma
Synapse
Postsynaptic Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Dendrite
Synapse
G Protein-coupled Serotonin Receptor Complex
Molecular Function
Actin Binding
Structural Molecule Activity
Protein Binding
Calmodulin Binding
Sodium Channel Regulator Activity
PDZ Domain Binding
Ion Channel Binding
Nitric-oxide Synthase Binding
ATPase Binding
Gq/11-coupled Serotonin Receptor Activity
G Protein-coupled Serotonin Receptor Activity
Protein Binding
Neurotransmitter Receptor Activity
Identical Protein Binding
Serotonin Binding
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding
Biological Process
Regulation Of Heart Rate
Regulation Of Vasoconstriction By Circulating Norepinephrine
Muscle Contraction
Neuromuscular Junction Development
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Ventricular Cardiac Muscle Cell Action Potential
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
Regulation Of Sodium Ion Transmembrane Transport
Behavioral Fear Response
Cellular Calcium Ion Homeostasis
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating Serotonin Receptor Signaling Pathway
Chemical Synaptic Transmission
Locomotory Behavior
Feeding Behavior
Positive Regulation Of Phosphatidylinositol Biosynthetic Process
CGMP-mediated Signaling
Regulation Of Nervous System Process
Regulation Of Appetite
Response To Drug
Regulation Of Corticotropin-releasing Hormone Secretion
Positive Regulation Of Fat Cell Differentiation
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways
Serotonin receptors
G alpha (q) signalling events
Drugs
Tramadol
Ziprasidone
Methysergide
Cabergoline
Amitriptyline
Olanzapine
Clozapine
Mirtazapine
Loxapine
Promazine
Cyproheptadine
Imipramine
Fluoxetine
Chlorpromazine
Chlorpromazine
Haloperidol
Nortriptyline
Amoxapine
Fenfluramine
Lisuride
Fluphenazine
Trazodone
Ergotamine
Apomorphine
Paroxetine
Trimipramine
Risperidone
Propiomazine
Minaprine
Cyclobenzaprine
Maprotiline
Ergoloid mesylate
Tegaserod
Doxepin
Nefazodone
Desipramine
Escitalopram
Pergolide
Dexfenfluramine
Bromocriptine
Ketamine
Quetiapine
Aripiprazole
Chlorprothixene
Clomipramine
Paliperidone
Yohimbine
Methotrimeprazine
Midomafetamine
4-Bromo-2,5-dimethoxyphenethylamine
Lorcaserin
Dapoxetine
Lofexidine
Epicept NP-1
Sertindole
Mianserin
Pizotifen
Asenapine
Ocaperidone
Dotarizine
Deramciclane
Agomelatine
Esmirtazapine
Captodiame
Etoperidone
Lorpiprazole
Setiptiline
Dihydroergocornine
m-Chlorophenylpiperazine
Gilteritinib
Sarpogrelate
Eplivanserin
Tiapride
Dihydroergocristine
2,5-Dimethoxy-4-ethylthioamphetamine
Aripiprazole lauroxil
Diseases
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
HDL cholesterol x physical activity interaction (1df test) (
30670697
)
HDL cholesterol x physical activity interaction (2df test) (
30670697
)
Interacting Genes
74 interacting genes:
ABCA1
ABCC4
ACTA2
ADAMTS6
ADGRB1
ADGRB2
ADGRB3
ADH5
ADRA1D
ADRA2A
ADRB1
AGTR2
ATP2B2
ATP6V0B
C3AR1
CALM1
CD3E
CNKSR2
COPB1
DGKZ
DMD
DTNA
DTNB
F8A1
FABP1
FAM189B
GDA
GLS
GLS2
GOLGA2
GRB2
GUCY1A2
HTR2B
HTR2C
IL2RA
IL9
ITGB5
KCNA4
KCNA5
KCNJ10
KCNJ12
KCNJ15
KCNJ4
KIF1B
LMO1
MAP4
MAPK12
MAS1
MAST1
MCM7
MED8
MTMR2
NAT1
NMU
NOS1
PFN2
PRLHR
PSKH1
RPS6KA1
SCN1A
SCN4A
SCN5A
SCTR
SLC16A7
SLC1A7
SLC2A3
SLC6A3
SSTR1
TGFA
TLX3
TRA
TRBV12-3
UTRN
XRCC6
34 interacting genes:
APBA1
ARRB2
ATP2B3
ATP6AP2
ATP6V0C
C4orf3
CALM1
CBX3
CNIH1
CRELD1
DLG4
EMP1
ERG28
GHITM
GJA1
GNAQ
GPR37
GPRC5B
LIN7C
MFSD14A
MPDZ
PLP1
RTN4
SGCB
SLC29A1
SLC39A1
SLC39A9
SNTA1
SPNS1
TM9SF2
TMBIM6
TMEM147
TMEM94
TPI1
Entrez ID
6640
3358
HPRD ID
03009
02429
Ensembl ID
ENSG00000101400
ENSG00000147246
Uniprot IDs
Q13424
K9J958
P28335
PDB IDs
6BQG
6BQH
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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