CANX and CD1D

Data Source:
HPRD (in vivo)

		CANX	CD1D
Description		calnexin	CD1d molecule
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Melanosome Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Presynapse	Extracellular Space Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Basolateral Plasma Membrane
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Unfolded Protein Binding	Protein Binding Beta-2-microglobulin Binding Lipid Antigen Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Histone Binding Cell Adhesion Molecule Binding Lipopeptide Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Folding Protein Secretion Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Synaptic Vesicle Endocytosis Interleukin-27-mediated Signaling Pathway Interleukin-35-mediated Signaling Pathway Clathrin-dependent Endocytosis	Positive Regulation Of T Cell Mediated Cytotoxicity Immune Response Detection Of Bacterium Heterotypic Cell-cell Adhesion Positive Regulation Of T Cell Proliferation T Cell Selection Innate Immune Response Positive Regulation Of Innate Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Immune Response
Pathways		Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate	cis-tetracosenoyl sulfatide
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Resting heart rate ( 24680774) White blood cell count ( 32888494 27863252)	Dental caries (decayed and filled deciduous teeth) ( 31533690)
Interacting Genes		47 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F2RL1 F8 FAM107A FSHR GPR35 GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LINC01554 LPA LRP1 LTB4R2 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR	7 interacting genes: B2M CALR CANX CD74 P4HB PTPRC TRB
Entrez ID		821	912
HPRD ID		00252	01780
Ensembl ID		ENSG00000127022	ENSG00000158473
Uniprot IDs		P27824	A0A669KAZ2 A0A669KB34 P15813
PDB IDs			1ZT4 2PO6 3HUJ 3SDX 3TZV 3U0P 3VWJ 3VWK 4EN3 4LHU 4MNG 4MQ7 4WO4 4WW2 4WWK 6V7Y 6V7Z 6V80
Enriched GO Terms of Interacting Partners?
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