CANX and HTR3A

Data Source:
HPRD (in vitro, in vivo)

		CANX	HTR3A
Description		calnexin	5-hydroxytryptamine receptor 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Melanosome Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Presynapse	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Cleavage Furrow Neuron Projection Neuronal Cell Body Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane Serotonin-activated Cation-selective Channel Complex
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Unfolded Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Serotonin-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Serotonin Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Folding Protein Secretion Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Synaptic Vesicle Endocytosis Interleukin-27-mediated Signaling Pathway Interleukin-35-mediated Signaling Pathway Clathrin-dependent Endocytosis	Signal Transduction Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Positive Regulation Of Ion Transmembrane Transporter Activity Ion Transmembrane Transport Response To Cocaine Regulation Of Membrane Potential Response To Ethanol Nervous System Process Cellular Response To Growth Factor Stimulus
Pathways		Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Neurotransmitter receptors and postsynaptic signal transmission
Drugs		Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate	Ziprasidone Methadone Olanzapine Clozapine Palonosetron Loxapine Amoxapine Lamotrigine Cisapride Paroxetine Procaine Trimipramine Rocuronium Dolasetron Granisetron Ethanol Ondansetron Alosetron Dopamine Memantine Ergoloid mesylate Bupropion Tubocurarine Ketamine Quetiapine Metoclopramide Aripiprazole Chlorprothixene Cilansetron Renzapride DDP733 DDP-225 Tapentadol Ticalopride Serotonin Cannabidiol Vortioxetine Ramosetron Setiptiline Dihydroergocornine Tropisetron Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Resting heart rate ( 24680774) White blood cell count ( 32888494 27863252)	Chronic kidney disease ( 26420894) Diisocyanate-induced asthma ( 25918132) Multiple sclerosis ( 31604244)
Interacting Genes		47 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F2RL1 F8 FAM107A FSHR GPR35 GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LINC01554 LPA LRP1 LTB4R2 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR	2 interacting genes: CANX HSPA5
Entrez ID		821	3359
HPRD ID		00252	08917
Ensembl ID		ENSG00000127022	ENSG00000166736
Uniprot IDs		P27824	B4E398 P46098
PDB IDs
Enriched GO Terms of Interacting Partners?
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