TSC22D4 and SACS

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TSC22D4	SACS
Description		TSC22 domain family member 4	sacsin molecular chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Mitochondrion Axon Dendrite Cell Body Fiber
	Molecular Function	Protein Binding	Hsp70 Protein Binding Chaperone Binding Proteasome Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Response To Osmotic Stress Negative Regulation Of Transcription, DNA-templated	Protein Folding Negative Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Platelet count ( 27863252) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Blood pressure (smoking interaction) ( 25189868) Hypothyroidism ( 22493691) Metabolite levels ( 23823483) Protein quantitative trait loci ( 18464913) Type 2 diabetes ( 23300278)
Interacting Genes		63 interacting genes: ABLIM1 AIFM1 APIP ARHGAP9 BLZF1 CBX8 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU CTNNAL1 ENKD1 FBXW7 FRMD6 FXR2 GOLGA2 GORASP2 KPNA2 KRT40 LBP LMO1 LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP MYO15B NIF3L1 NOC4L NRBP1 NRBP2 PCBP1 PCDH17 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 RACK1 SACS SAT1 SMAD3 SMARCB1 SYT17 TEX11 TLE5 TRIM55 TRIM63 TSC22D1 TSPOAP1 UBLCP1 VBP1 ZBTB24 ZMYND10 ZNF580	6 interacting genes: ACTN4 ADRB2 PICK1 POLR1H TSC22D4 UBE3A
Entrez ID		81628	26278
HPRD ID		18231	05135
Ensembl ID		ENSG00000166925	ENSG00000151835
Uniprot IDs		B4DKI8 Q9Y3Q8	Q9NZJ4
PDB IDs			1IUR 3O10 5V44 5V45 5V46 5VSX 5VSZ
Enriched GO Terms of Interacting Partners?
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