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TSC22D4 and LBP
Data Source:
BioGRID
(two hybrid)
TSC22D4
LBP
Description
TSC22 domain family member 4
lipopolysaccharide binding protein
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Extracellular Region
Extracellular Space
Cell Surface
Membrane
Extracellular Exosome
Molecular Function
Protein Binding
Lipopolysaccharide Binding
Signaling Receptor Binding
Protein Binding
Lipoteichoic Acid Binding
Lipopeptide Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Negative Regulation Of Transcription, DNA-templated
Toll-like Receptor Signaling Pathway
Leukocyte Chemotaxis Involved In Inflammatory Response
Macrophage Activation Involved In Immune Response
Acute-phase Response
Cellular Defense Response
Opsonization
Lipopolysaccharide Transport
Cytokine-mediated Signaling Pathway
Lipopolysaccharide-mediated Signaling Pathway
Detection Of Molecule Of Bacterial Origin
Response To Lipopolysaccharide
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Macromolecule Localization
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Macrophage Activation
Innate Immune Response
Positive Regulation Of Cytolysis
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Regulation Of Respiratory Burst Involved In Inflammatory Response
Cellular Response To Lipopolysaccharide
Cellular Response To Lipoteichoic Acid
Positive Regulation Of Neutrophil Chemotaxis
Pathways
Toll Like Receptor 4 (TLR4) Cascade
Transfer of LPS from LBP carrier to CD14
Regulation of TLR by endogenous ligand
Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Platelet count (
27863252
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Basophil percentage of white cells (
32888494
)
Blood protein levels (
29875488
)
Periodontitis (DPAL) (
24024966
)
Interacting Genes
63 interacting genes:
ABLIM1
AIFM1
APIP
ARHGAP9
BLZF1
CBX8
CCDC146
CCDC33
CCDC42
CCNK
CDC23
CDK5R1
CKS2
CLU
CTNNAL1
ENKD1
FBXW7
FRMD6
FXR2
GOLGA2
GORASP2
KPNA2
KRT40
LBP
LMO1
LMO2
LNX1
LRP2BP
MAD2L1
MTHFS
MYLIP
MYO15B
NIF3L1
NOC4L
NRBP1
NRBP2
PCBP1
PCDH17
PIH1D1
PIN1
POLR1C
PPL
PRKAA1
PRKAA2
PRNP
PSMA1
RACK1
SACS
SAT1
SMAD3
SMARCB1
SYT17
TEX11
TLE5
TRIM55
TRIM63
TSC22D1
TSPOAP1
UBLCP1
VBP1
ZBTB24
ZMYND10
ZNF580
18 interacting genes:
APOA1
BAG6
BST1
C4BPA
CAMP
CBFA2T2
CD14
CFHR1
FTH1
HSPB1
PRDX4
PSMA3
PYCR3
RPS21
SETD1A
SMAD3
TRA2A
TSC22D4
Entrez ID
81628
3929
HPRD ID
18231
07175
Ensembl ID
ENSG00000166925
ENSG00000129988
Uniprot IDs
B4DKI8
Q9Y3Q8
P18428
Q8TCF0
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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