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TSC22D4 and LMO2
Data Source:
BioGRID
(two hybrid)
TSC22D4
LMO2
Description
TSC22 domain family member 4
LIM domain only 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Molecular Function
Protein Binding
RNA Polymerase II Activating Transcription Factor Binding
Transcription Coregulator Binding
Transcription Coactivator Activity
Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Negative Regulation Of Transcription, DNA-templated
Multicellular Organism Development
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS
Brain morphology (MOSTest) (
32665545
)
Platelet count (
27863252
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Cognitive performance (
19734545
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Iron status biomarkers (transferrin saturation) (
28334935
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
63 interacting genes:
ABLIM1
AIFM1
APIP
ARHGAP9
BLZF1
CBX8
CCDC146
CCDC33
CCDC42
CCNK
CDC23
CDK5R1
CKS2
CLU
CTNNAL1
ENKD1
FBXW7
FRMD6
FXR2
GOLGA2
GORASP2
KPNA2
KRT40
LBP
LMO1
LMO2
LNX1
LRP2BP
MAD2L1
MTHFS
MYLIP
MYO15B
NIF3L1
NOC4L
NRBP1
NRBP2
PCBP1
PCDH17
PIH1D1
PIN1
POLR1C
PPL
PRKAA1
PRKAA2
PRNP
PSMA1
RACK1
SACS
SAT1
SMAD3
SMARCB1
SYT17
TEX11
TLE5
TRIM55
TRIM63
TSC22D1
TSPOAP1
UBLCP1
VBP1
ZBTB24
ZMYND10
ZNF580
188 interacting genes:
ABI2
ADAMTSL4
AFDN
AGTRAP
AIMP2
ALDH6A1
ARHGEF5
ARID5A
ARNT2
AXIN1
BANP
BCAS2
BEX2
BLZF1
BYSL
C1orf109
C1orf94
CALCOCO2
CBY2
CCDC33
CDC25A
CDC5L
CDX4
CLHC1
CMTM5
CORO1A
CORO1C
DAZAP2
DBF4B
DDIT3
DMRT3
DRAP1
DYDC1
EFHC1
EFHC2
EHMT2
EIF3B
EIF4EBP1
ELF2
ENKD1
ERBIN
FAAP20
FAM214B
FAM228A
FAM90A1
FHL3
FHL5
GAS8
GATA1
GATA2
GATA3
GFAP
GMEB2
GOLGA2
GRB2
HDAC5
HNRNPC
HNRNPM
HOOK1
ICA1L
IFT43
IHO1
IKZF1
IKZF3
INCA1
ISL1
ISY1
KANK2
KAZN
KDM5A
KIF2A
KIF3B
KPRP
KRT15
KRT34
KRT40
KRT75
KRT80
KRTAP10-7
LDB1
LDB2
LDOC1
LMO4
LMOD3
LYL1
LZTS1
LZTS2
MAGEA8
MAPRE1
MAPRE2
MAPRE3
MBIP
MISP
MRFAP1L1
MSN
MTUS2
MYOZ3
N4BP2L2
NCAPH2
NDOR1
NDUFAB1
NDUFB7
NFKBID
NHLH1
NIF3L1
NOTCH2NLA
NOXA1
NSMF
NTAQ1
NUP62
NUTM1
PATZ1
PAX9
PBX4
PDE9A
PHC2
POLR2G
PPP1R32
PRDM6
PRKG1
PSMA1
RBBP8
RCN1
REL
RELA
RINT1
RLIM
ROCK1
RTL8C
RUSC1
SAXO1
SGTB
SKP1
SMAD2
SMUG1
SNAPC5
SOX5
SP1
SSX2IP
STAT1
STAT3
STIP1
TAL1
TAL2
TBX2
TCP10L
TEKT3
TFIP11
TFPT
THAP6
TLE5
TLX3
TRIB3
TRIM23
TRIM54
TRIM55
TRIM63
TRIP6
TSC1
TSC22D4
TSEN15
TSEN54
TSGA10IP
TSPYL2
TSSK3
TUFT1
UBA6
UBASH3B
UBE2I
USH1G
VBP1
VEZF1
VMAC
WASF1
WASHC1
YOD1
YPEL3
ZFP64
ZMYND12
ZNF185
ZNF19
ZNF24
ZNF250
ZNF34
ZNF410
ZNF641
ZNF655
ZNF688
Entrez ID
81628
4005
HPRD ID
18231
01586
Ensembl ID
ENSG00000166925
ENSG00000135363
Uniprot IDs
B4DKI8
Q9Y3Q8
P25791
PDB IDs
2XJY
2XJZ
2YPA
4KFZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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