SETD7 and A1BG

Data Source:
BioGRID (two hybrid)

		SETD7	A1BG
Description		SET domain containing 7, histone lysine methyltransferase	alpha-1-B glycoprotein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Secretory Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	P53 Binding Chromatin Binding Protein Binding Protein-lysine N-methyltransferase Activity Histone-lysine N-methyltransferase Activity	Molecular_function
	Biological Process	Chromatin Organization Cellular Response To DNA Damage Stimulus Peptidyl-lysine Monomethylation Peptidyl-lysine Dimethylation Histone Lysine Methylation Response To Ethanol Positive Regulation Of Transcription, DNA-templated Regulation Of Histone H3-K9 Methylation Heterochromatin Organization	Platelet Degranulation Biological_process Neutrophil Degranulation
Pathways		PKMTs methylate histone lysines	Platelet degranulation Neutrophil degranulation
Drugs		S-adenosyl-L-homocysteine	Zinc Copper Zinc acetate
Diseases
GWAS		Diastolic blood pressure in combination therapy (beta blocker and thiazide diuretic) ( 29097388) Lean body mass ( 28552196) Salty taste perception in obesity with metabolic syndrome ( 31005965) Serum lycopene concentrations ( 26861389)
Interacting Genes		29 interacting genes: A1BG ATG16L1 DNMT1 E2F1 ESR1 H3-3A H3-4 H3C1 H3C14 H4C1 HCFC1 KLF4 L3MBTL1 MDM2 NR2F2 PPP1R12A PRKAR1A RELA RIOK1 SERTAD1 SIRT1 SMAD7 SOX2 STAT3 STEAP3 TAF10 TAF7 TP53 TRIM21	10 interacting genes: ABCC6 ANXA7 CDKN1A CRISP3 GRB7 PRDX4 SETD7 SMN1 SNCA TK1
Entrez ID		80854	1
HPRD ID		16226	00726
Ensembl ID		ENSG00000145391	ENSG00000121410
Uniprot IDs		B5MCZ8 D6RJA0 Q8WTS6	P04217 V9HWD8
PDB IDs		1H3I 1MT6 1MUF 1N6A 1N6C 1O9S 1XQH 2F69 3CBM 3CBO 3CBP 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 3OS5 3VUZ 3VV0 4E47 4J7F 4J7I 4J83 4J8O 4JDS 4JLG 5AYF 5EG2 5YLT
Enriched GO Terms of Interacting Partners?
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