PTP4A2 and RABGGTB

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PTP4A2	RABGGTB
Description		protein tyrosine phosphatase 4A2	Rab geranylgeranyltransferase subunit beta
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GO Annotations	Cellular Component	Nucleus Cytoplasm Early Endosome Cytosol Plasma Membrane	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	Protein Tyrosine Phosphatase Activity Prenylated Protein Tyrosine Phosphatase Activity Protein Binding	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation Post-translational Protein Modification	Cellular Protein Modification Process Visual Perception Protein Phosphopantetheinylation Protein Prenylation Protein Geranylgeranylation Regulation Of Apoptotic Process Post-translational Protein Modification
Pathways		RAB geranylgeranylation	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs			N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Body mass index ( 26426971)	Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)
Interacting Genes		4 interacting genes: ATF7 CNNM1 CNNM3 RABGGTB	20 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA SH3GLB1 TAFA1 TMEM25 WDR4
Entrez ID		8073	5876
HPRD ID		03348	01532
Ensembl ID		ENSG00000184007	ENSG00000137955
Uniprot IDs		Q12974	A8KAJ2 P53611 Q6IB63
PDB IDs		5K22 5K23 5K25 6WUR	6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?
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