RABGGTB and WDR4

Data Source:
BioGRID (two hybrid, two hybrid)

		RABGGTB	WDR4
Description		Rab geranylgeranyltransferase subunit beta	WD repeat domain 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex	Nucleus Nucleoplasm Chromosome Cytosol TRNA Methyltransferase Complex
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Small GTPase Binding	Protein Binding TRNA (guanine-N7-)-methyltransferase Activity
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Phosphopantetheinylation Protein Prenylation Protein Geranylgeranylation Regulation Of Apoptotic Process Post-translational Protein Modification	TRNA Modification Cellular Response To DNA Damage Stimulus TRNA (guanine-N7)-methylation
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation	tRNA modification in the nucleus and cytosol
Drugs		N-Formylmethionine Farnesyl diphosphate Geranylgeranyl diphosphate
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)	Blood and toenail selenium levels ( 25343990) Fasting plasma glucose ( 28270201)
Interacting Genes		20 interacting genes: ALAS2 ARAF B4GALT7 CHML IGFBP6 NPSR1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A RABGGTA SH3GLB1 TAFA1 TMEM25 WDR4	6 interacting genes: FAM118A FEN1 METTL1 RABGGTB TERF1 TERF2
Entrez ID		5876	10785
HPRD ID		01532	09330
Ensembl ID		ENSG00000137955	ENSG00000160193
Uniprot IDs		A8KAJ2 P53611 Q6IB63	P57081
PDB IDs		6J6X 6J74 6J7F 6J7X 6O60
Enriched GO Terms of Interacting Partners?
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