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ADAM12 and KRTAP4-12
Data Source:
BioGRID
(two hybrid)
ADAM12
KRTAP4-12
Description
ADAM metallopeptidase domain 12
keratin associated protein 4-12
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Nucleoplasm
Plasma Membrane
Integral Component Of Membrane
Keratin Filament
Molecular Function
Metalloendopeptidase Activity
Protein Binding
Metallopeptidase Activity
SH3 Domain Binding
Metal Ion Binding
Protein Binding
Biological Process
Proteolysis
Cell Adhesion
Myoblast Fusion
Extracellular Matrix Organization
Positive Regulation Of Angiogenesis
Pathways
Signaling by EGFR
Invadopodia formation
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Endometrial cancer (
24096698
)
Extremely high intelligence (
29731509
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
30054594
)
Itch intensity from mosquito bite (
28199695
)
Loneliness (
27629369
)
Metabolite levels (5-HIAA/ MHPG Ratio) (
23319000
)
Mild influenza (H1N1) infection (
26379185
)
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder (
26184070
27021288
)
Placental abruption (
29884306
)
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Visceral fat (
22589738
)
Interacting Genes
40 interacting genes:
ACTN2
ADAMTSL4
CYSRT1
EGF
ESM1
FHL5
FSTL3
GRB2
GUCD1
HOXA1
IGFBP3
IGFBP5
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-8
KRTAP12-2
KRTAP3-1
KRTAP3-2
KRTAP4-12
KRTAP5-6
KRTAP5-9
KRTAP6-2
KRTAP9-2
KRTAP9-8
LCE5A
MAPKBP1
NBPF19
NOTCH2NLA
OTX1
PACSIN3
PIK3R1
RECK
SH3D19
SLC15A2
SPRY1
SPRY4
SRC
TFAP2D
YES1
152 interacting genes:
ADAM12
ADAMTSL4
ALPP
AQP1
ATG12
ATN1
AXIN1
BAG4
BAHD1
BEX2
C10orf62
CATSPER1
CBX2
CCDC116
CCDC185
CCNK
CDC42EP1
CDX2
CHCHD3
CHIC2
CHRD
CLCNKA
CLDN2
CNNM3
CNTFR
COL8A1
CRCT1
CREB5
CRY1
CYSRT1
DBF4B
DLK2
EIF4E2
ELOA2
FAM107A
FAM27E3
FAM76B
FBXL18
FBXO34
FBXW5
FCHO1
FUCA2
GLRX3
GNE
GPATCH2L
GPRIN2
GRAP2
HHEX
HOXA1
HOXB9
IFI30
IGSF8
ILF3
KRT31
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP19-2
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP3-1
KRTAP3-2
KRTAP5-1
KRTAP5-6
KRTAP5-9
KRTAP6-2
KRTAP9-2
KRTAP9-3
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LELP1
LINGO1
LNX1
MAPKBP1
MEOX2
MRPL4
NOTCH2NLA
NPDC1
NUDT18
NUFIP2
OTX1
PCSK5
PDGFRB
PFKL
PHLDA1
PLSCR1
PLSCR4
PNKP
POU4F2
PRKAB2
PRKAG1
PRR13
PTPMT1
QPRT
R3HDM2
RERE
RPS28
SHFL
SLC25A10
SLC25A6
SMCP
SPATA3
SPG7
SPRY1
SPRY2
TAP1
TBC1D16
TBC1D23
TGM1
THAP10
THAP7
TOP3B
TXNDC5
ZBTB16
ZNF165
ZNF20
ZNF250
ZNF408
ZNF414
ZNF415
ZNF417
ZNF426
ZNF439
ZNF440
ZNF497
ZNF581
ZNF638
ZNF655
ZNF696
ZNF764
ZNF837
ZSCAN26
Entrez ID
8038
83755
HPRD ID
04092
13941
Ensembl ID
ENSG00000148848
ENSG00000213416
Uniprot IDs
A8K6G4
O43184
U5NE98
Q9BQ66
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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